A New Drug Shows Promise for Hard-to-Treat High Blood Pressure

B2 – Upper Intermediate

The drug, called baxdrostat, was tested in people with treatment-resistant hypertension (high blood pressure that doesn’t respond well to existing medicines). In the trial, those taking baxdrostat plus standard medication had their systolic blood pressure fall about 9-10 mmHg more than people on placebo.

Read the article to know more about baxdrostat.

Vocabulary Questions:

  1. What does “resistant hypertension” mean? “The results of a large clinical trial, published August 30 in the New England Journal of Medicine, suggest that baxdrostat could offer an alternative for people with resistant hypertension.” Use it in a sentence.
  2. What does “hyperfiltration” mean? “Kidney effects were minor and may even be beneficial, he says, because they may reduce harmful hyperfiltration. Use it in a sentence.
  3. What does “withdrawal phase” mean in a clinical trial? “The trial also included an eight-week withdrawal phase.” Use it in a sentence.

Discussion Questions:

  1. What are the potential benefits of baxdrostat? How about the What are the concerns and side effects?
  2. Share your thoughts on this, “Hypertension, or high blood pressure, is a serious condition where blood pressure is consistently too high, affecting over 1.2 billion adults globally.
  3. Why do you think it is important to keep find new hypertension medicines?
  4. What are some ways people can lower their blood pressure without medicine?
  5. Do you know anyone who struggles with hypertension? How is it like for them?
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