B1 – Intermediate
Because of a new experimental gene therapy, cancer patients might have a fighting chance against the deadly disease cancer.
Gene therapy is a medical approach to treat or cure a person from a disease by modifying their genes. The process involves replacing defective genes with healthy ones.
For more than ten years of his life Nick Wilkins fought leukemia. It was a heartbreaking time for his parents. But now at 15, Nick is cancer-free thanks to a new experimental therapy.
Nick went through many kinds of treatment: chemotherapy, radiation therapy and a bone marrow transplant, but the cancer kept coming back. Nothing was working. But then his parents found out about a clinical trial for an experimental gene therapy at the University of Pennsylvania.
It’s called “personalized cell therapy.” Doctors reprogram the patient’s T-cells to multiply and then attack and destroy cancer cells. The T-cells attack the cancer cells like the body fights a cold.
Trials started in 2010 and the results have been very positive. Most of the children in the trials have gone into complete remission. And one third of adults have gone into remission, as well.
There are plans to expand the trials to other hospitals. If all goes well the treatment could become available to the public in three to five years.
Discussion Questions:
- What was your reaction to the success of this approach with Nick Wilkins?
- What are your thoughts on gene therapy or personalized cell therapy?
- What are the good and bad things about being a part of a clinical trial for an experimental drug or treatment?
- If you were Nick Wilkins’ parents, would you do the same with your child who is suffering from a terminal illness? Why or why not?
- Why do you think it is so hard to find an ultimate cure for cancer?