B2 – Upper Intermediate
A recent clinical trial found that a popular weight-loss drug significantly reduces the risk of early death in patients with heart failure. This adds to the drug’s potential benefits beyond weight loss, such as improved cardiovascular outcomes.
Read the article to know the other benefits of semaglutide.
https://www.ajmc.com/view/patients-with-heart-failure-may-benefit-from-weight-loss-drug
Vocabulary Questions:
- What does “ejection fraction” mean? “Focusing on the 4286 patients with heart failure at enrollment, 53% had heart failure with preserved ejection fraction (HFpEF), 31.4% had heart failure with reduced ejection fraction (HFrEF), and 15.5% had unspecified heart failure.” Use it in a sentence.
- What does “baseline characteristics” mean? “While baseline characteristics were similar between patients with and without heart failure, those with heart failure had a higher incidence of clinical events.” Use it in a sentence.
- What does “composite” mean here, “We showed, for the first time to our knowledge, that patients with atherosclerotic cardiovascular disease, overweight or obesity, and heart failure with reduced ejection fraction (who had a greatest absolute risk) had significant reductions in MACE with semaglutide, and the treatment effect on the heart failure composite was observed to be similar to that seen in the population with heart failure with preserved ejection fraction.” Use it in a sentence.
Discussion Questions:
- Did you know that a weight-loss drug could reduce the risk of early death in heart failure patients? How do you think this could change treatment approaches?
- What might be the benefits of using medications for dual purposes, like weight loss and cardiovascular health?
- Why do you think weight management plays such an important role in heart health?
- Do you think medications like this could become a standard part of heart failure treatment in the future? Why or why not?